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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO34
All Species:
11.82
Human Site:
S253
Identified Species:
32.5
UniProt:
Q9NWN3
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWN3
NP_060413.2
711
78711
S253
P
A
V
S
E
S
Y
S
A
P
G
A
C
E
E
Chimpanzee
Pan troglodytes
XP_509963
826
91671
S368
P
A
V
S
E
S
Y
S
A
P
G
A
C
E
E
Rhesus Macaque
Macaca mulatta
XP_001086106
773
85371
E314
R
G
V
P
A
A
T
E
S
C
S
A
P
G
A
Dog
Lupus familis
XP_547825
711
79010
S253
L
S
A
S
E
P
F
S
A
P
G
A
C
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80XI1
695
77119
S252
P
P
A
P
E
P
F
S
A
P
E
T
C
E
E
Rat
Rattus norvegicus
Q4KLY2
603
65220
P160
T
P
A
T
E
V
A
P
T
S
S
G
D
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026384
745
81040
A282
P
S
S
D
P
F
S
A
A
G
P
C
E
V
H
Frog
Xenopus laevis
NP_001091412
677
75143
T234
R
Q
T
D
K
D
S
T
E
Q
T
D
Q
M
E
Zebra Danio
Brachydanio rerio
XP_002665197
726
81445
E258
L
Q
Q
E
A
H
C
E
N
I
N
P
C
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
88.8
85.5
N.A.
71.7
32.4
N.A.
N.A.
57.7
46.9
30.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
85.7
90.1
90.5
N.A.
80.5
44.8
N.A.
N.A.
67.5
61.8
44.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
66.6
N.A.
53.3
6.6
N.A.
N.A.
13.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
80
N.A.
60
20
N.A.
N.A.
26.6
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
34
0
23
12
12
12
56
0
0
45
0
0
12
% A
% Cys:
0
0
0
0
0
0
12
0
0
12
0
12
56
0
0
% C
% Asp:
0
0
0
23
0
12
0
0
0
0
0
12
12
12
0
% D
% Glu:
0
0
0
12
56
0
0
23
12
0
12
0
12
45
56
% E
% Phe:
0
0
0
0
0
12
23
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
0
0
0
0
0
12
34
12
0
12
12
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% N
% Pro:
45
23
0
23
12
23
0
12
0
45
12
12
12
0
0
% P
% Gln:
0
23
12
0
0
0
0
0
0
12
0
0
12
12
0
% Q
% Arg:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
23
12
34
0
23
23
45
12
12
23
0
0
0
0
% S
% Thr:
12
0
12
12
0
0
12
12
12
0
12
12
0
0
0
% T
% Val:
0
0
34
0
0
12
0
0
0
0
0
0
0
12
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _